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Prolonged breastfeeding helps prevent rheumatoid arthritis
Seeking more conclusive evidence, a team of researchers led by Dr. Elizabeth Karlson at Brigham and Women's Hospital in Boston drew on a large sample – 121,700 women – to explore the contribution of hormonal factors occurring prior to the onset of RA and the impact of postmenopausal hormone replacement therapy on the risk of disease Their findings, published in the November 2004 issue of Arthritis & Rheumatism, strongly support the lasting benefits of breastfeeding in protecting against the disease. What's more, the researchers identified a new risk factor for RA: irregular menstrual cycles.
The study's subjects were all women enrolled in the Nurses' Health Study, a sweeping investigation of disease, health, and lifestyle, ongoing since 1976. Through extensive questionnaires, the research team documented each woman's reproductive history with attention to potential RA risk factors, including age at menarche, age at first birth, history of breastfeeding, use of oral contraceptives, and regularity of menstrual cycles and in older women studied the use of estrogen after menopause. Among these women, the researchers confirmed 674 RA patients, diagnosed anywhere between 1976 and 2002. Most of the women were middle-aged at disease onset; the mean age was 56 years.
Upon analyzing the data, adjusting for variables such age and cigarette smoking, the researchers noted several interesting trends. One of the strongest was a decreasing risk of RA with increasing duration for breastfeeding. Looking at total lifetime breastfeeding, regardless of number of children, women who had breast-fed for between 13 and 23 months had a 20 percent reduction in the risk of RA compared with women who did not breastfeed. Women who had breast-fed for at least 24 months – two full years out of their childbearing years – increased their risk reduction to 50 percent. "Our data suggest breast-feeding confers long lasting protection against developing RA," Dr. Karlson states, "because the mean time since the last pregnancy among women with RA was 25 years."
In addition, women who experienced irregular menstrual cycles between the ages of 20 and 35 were shown to have an increased risk of subsequent RA. Women who had begun menstruating at an early age, 10 or younger, were more likely to develop seropositive RA. The study's results did not show any association between a history of oral contraceptive use and disease risk, or any significant differences in disease risk related to a woman's number of pregnancies.
Focusing on the sample of RA patients, compared to women who did not develop RA, the researchers confirmed that the risk of RA increases with age and demonstrated a peak risk at the typical time of menopause, age 50 to 54. Because the onset of RA often coincides with menopause, some studies have linked the disease to falling estrogen levels, indicating the potential benefits of estrogen therapy. In this study, however, estrogen therapy among postmenopausal women did not protect against RA.
"These findings suggest avenues for further research into the hormonal mechanisms involved in RA, because the complex relationships between RA and reproductive hormones clearly warrant further study," Dr. Karlson concludes.
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"Breastfeeding is a gift of love from mother to child." -A sig at Mothering
~Tuesday is Chat day~
~From our message board~
~Secret Santa info~
~Recipe of the month~
Apple Cream Crumble Pie
1 Single Crust Recipe of Your Favorite Pie Crust Prepare piecrust. Roll out to 12-inch circle; fit into a 9-inch pie plate. Trim overhang to ½ inch, turn under flush with rim, and flute. Pare, quarter and core apples, then halve each quarter crosswise. (You should have about 7 cups.) Place in large bowl; sprinkle lemon juice over. Mix ½ c. sugar, 2 tbsp flour, and nutmeg in a cup. Sprinkle over apples, tossing to coat well; spoon into prepared shell. Combine ½ c. sugar and 1/3 c. flour in small bowl. Cut in butter or margarine until crumbly; sprinkle over apples. Cover pie loosely with foil. Place on large cookie sheet for easy handle (and to catch drips!). Bake in 425 degree oven for 45 minutes; uncover and drizzle ½ c. cream over pie. Bake 15 minutes longer, until pie is golden. Remove pie from oven and place on wire rack. Drizzle remaining ½ c. cream over top. Cool about 1 hour or until filling is set. Note: This pie gets very messy because the cream invariable drips over the side. But it is SOOO worth it—it’s the best apple pie I’ve ever had!
Ms. Frizzle
What is your earliest memory of breastfeeding?
Where did you grow up?
What is your dream job?
How do family and friends react to your nursing?
Do you have problems nursing in public or in front of people?
What is your favorite thing about being a mom?
~Parenting humor~
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If you knew It was Poison, Would you Still Buy It? Remove the toxic Chemicals From your Home. Its Simple! Switch Stores for better, safer, non toxic products.
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We are looking for breastfeeding stories, birth stories, and photos for our nursing photo album. Please email submissions to Ms. Frizzle or Quinn
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